Efforts by governments, firms, and patients to deliver pioneering drugs for critical health needs face a challenge of diminishing efficiency in developing those medicines. While multi-sectoral collaborations involving firms, researchers, patients, and policymakers are widely recognized as crucial for countering this decline, existing incentives to engage in drug development predominantly target drug manufacturers and thereby do little to stimulate collaborative innovation. In this mini review, we consider the unexplored potential within pharmaceutical regulations to create novel incentives to encourage a diverse (...) set of actors from the public and private spheres to engage in the kind of collaborative knowledge exchange requisite for fostering enhanced innovation in early drug development. (shrink)

This anthology offers a comprehensive introduction to Pliny the Younger's Epistulae for intermediate and advanced Latin students, with the grammatical, lexical, and historical support to enable them to read quickly and fluidly. As the only selection of the letters with extensive commentary, it provides instructors with a unique and complete resource for students.ABOUT THE SERIESThe Oxford Greek and Latin College Commentaries is designed for students in intermediate or advanced Greek or Latin. Each volume includes a comprehensive introduction. The placement, on (...) the same page, of the ancient text, a running vocabulary, and succinct notes focusing on grammar, syntax, and distinctive features of style provides students with essential learning aids.Series Editors: Barbara Weiden Boyd, Bowdoin College, Stephen Esposito, Boston University, and Mary Lefkowitz, Wellesley CollegeAlso Available Ovid: Ars Amatoria, Book 3, Christopher M. Brunelle, St. Olaf CollegeForthcoming Latin VolumesSuetonius's Life of AugustusDarryl Phillips, Connecticut CollegeLucan's De Bello Civile, Book 5Jonathan Tracy, Massey University, New Zealand. (shrink)

One might be inclined to assume, given the mouse donning its cover, that the behavior of interest in Nicole Nelson's book Model Behavior (2018) is that of organisms like mice that are widely used as “stand-ins” for investigating the causes of human behavior. Instead, Nelson's ethnographic study focuses on the strategies adopted by a community of rodent behavioral researchers to identify and respond to epistemic challenges they face in using mice as models to understand the causes of disordered human behaviors (...) associated with mental illness. Although Nelson never explicitly describes the knowledge production activities in which her behavioral geneticist research subjects engage as “exemplary”, the question of whether or not these activities constitute “model behavior(s)”—generalizable norms for engaging in scientific research—is one of the many thought-provoking questions raised by her book. As a philosopher of science interested in this question, I take it up here. (shrink)

In his correspondence, John Locke described his close friend Damaris Masham as ‘a determined foe to ecclesiastical tyranny’ and someone who had ‘the greatest aversion to all persecution on account of religious matters.’ In her short biography of Locke, Masham returned the compliment by commending Locke for convincing others that ‘Liberty of Conscience is the unquestionable Right of Mankind.’ These comments attest to Masham’s personal commitment to the cause of religious liberty. Thus far, however, there has been no scholarly discussion (...) of the tolerationist ethic underlying Masham’s 1705 publication, Occasional Thoughts. In this chapter, I argue that Masham’s work appeals to three common tolerationist principles of her time: the idea that the authorities should not use coercion and penalties as ways of imposing religious beliefs on others; the view that God requires human beings to attain salvation through their own efforts, and not by blindly following the dictates of the state-established religion; and the idea that the granting of liberty of conscience helps to ensure the peace and stability of political society. I show that Masham goes further than her tolerationist contemporaries by arguing that together these principles imply that a woman’s intellectual education—or the conscious cultivation of a woman’s ability to reflect critically on her religious beliefs—is vital for the good of the commonwealth. (shrink)

Ian Hacking instigated a revolution in 20th century philosophy of science by putting experiments (“interventions”) at the top of a philosophical agenda that historically had focused nearly exclusively on representations (“theories”). In this paper, I focus on a set of conceptual tools Hacking (1992) put forward to understand how laboratory sciences become stable and to explain what such stability meant for the prospects of unity of science and kind discovery in experimental science. I first use Hacking’s tools to understand sources (...) of instability and disunity in rodent behavioral neuroscience. I then use them to understand recent grass-roots collaborative open science initiatives aimed at establishing stability in this research area and tease out some implications for unity of science and kind creation and discovery in cognitive neuroscience. -/- . (shrink)

Abstract: In this paper, I respond to James Sterba’s recent book ‘Is a Good God Logically Possible?’ I show that Sterba concludes that God is not logically possible by ignoring three important issues: (a) the different functions of leeway indeterminism (and the political freedom presupposed by it) and autonomy (the two are very different things, even though both go under the name of freedom), (b) the differences in the conditions of agency in God and in creatures, (there is non-parity in (...) how each must apply the single moral law), and (c) the non-parity between our knowledge and God’s. I provide a brief summary of Sterba’s arguments, and I develop the following points: 1. Sterba’s argument against a Free-Will Defense hinges on his conflation of political freedom and autonomy; 2. Sterba’s crucial premise for his argument against soul-making theodicies (namely, that the “Pauline Principle” should be applied univocally across God and creatures) is false; 3. Sterba’s arguments against skeptical theism depend on his assumption that our knowledge is comparable to that of God. In each case, Sterba either does not recognize non-parity between God and creatures or does not recognize the difference between the profane (e.g., political matters) and the sacred, (e.g., spiritual matters having to do with the inner nature of the soul’s development). (shrink)

A critic of utilitarianism, in a paper entitled “Innocence and Consequentialism” Laing argues that Singer cannot without contradicting himself reject baby farming (a thought experiment that involves mass-producing deliberately brain damaged children for live birth for the greater good of organ harvesting) and at the same time hold on to his “personism” a term coined by Jenny Teichman to describe his fluctuating (and Laing says, discriminatory) theory of human moral value. His explanation that baby farming undermines attitudes of care and (...) concern for the very young, can be applied to babies and the unborn (non-persons on his view) and contradicts positions that he adopts elsewhere in his work. (shrink)

As citizens, we hold certain truths to be self-evident: that the rights to own land, marry, inherit property, and especially to assume birthright citizenship should be guaranteed by the state. The laws promoting these rights appear not only to preserve our liberty but to guarantee society remains just. Yet considering how much violence and inequality results from these legal mandates, Jacqueline Stevens asks whether we might be making the wrong assumptions. Would a world without such laws be more just? (...) Arguing that the core laws of the nation-state are more about a fear of death than a desire for freedom, Jacqueline Stevens imagines a world in which birthright citizenship, family inheritance, state-sanctioned marriage, and private land ownership are eliminated. Would chaos be the result? Drawing on political theory and history and incorporating contemporary social and economic data, she brilliantly critiques our sentimental attachments to birthright citizenship, inheritance, and marriage and highlights their harmful outcomes, including war, global apartheid, destitution, family misery, and environmental damage. It might be hard to imagine countries without the rules of membership and ownership that have come to define them, but as Stevens shows, conjuring new ways of reconciling our laws with the condition of mortality reveals the flaws of our present institutions and inspires hope for moving beyond them. (shrink)

As citizens, we hold certain truths to be self-evident: that the rights to own land, marry, inherit property, and especially to assume birthright citizenship should be guaranteed by the state. The laws promoting these rights appear not only to preserve our liberty but to guarantee society remains just. Yet considering how much violence and inequality results from these legal mandates, Jacqueline Stevens asks whether we might be making the wrong assumptions. Would a world without such laws be more just? (...) Arguing that the core laws of the nation-state are more about a fear of death than a desire for freedom, Jacqueline Stevens imagines a world in which birthright citizenship, family inheritance, state-sanctioned marriage, and private land ownership are eliminated. Would chaos be the result? Drawing on political theory and history and incorporating contemporary social and economic data, she brilliantly critiques our sentimental attachments to birthright citizenship, inheritance, and marriage and highlights their harmful outcomes, including war, global apartheid, destitution, family misery, and environmental damage. It might be hard to imagine countries without the rules of membership and ownership that have come to define them, but as Stevens shows, conjuring new ways of reconciling our laws with the condition of mortality reveals the flaws of our present institutions and inspires hope for moving beyond them. (shrink)

This article sits at a point of intersection between the philosophy of physics and the metaphysics of modality. There are clear similarities between Everettian quantum mechanics and various modal metaphysical theories, but there have hitherto been few attempts at exploring how the two topics relate. In this article, I build on a series of recent papers by Wilson ([2011], [2012], [2013]), who argues that Everettian quantum mechanics’ connections with traditional modal metaphysics are vital in defending it against objections. I show (...) that Wilson’s preferred version of Everettian quantum mechanics has two problems. First, it is unable to account for the contingency of various intuitively contingent modal claims. Second, it fails to yield intuitive truth values on modal claims about the number of branches in a given Everettian multiverse. Since modal claims about branch number are instrumental in decision-theoretic solutions to Everettian quantum mechanics’ problem(s) with probability, this second problem has wider dialectical implications. I suggest amendments to the underlying metaphysics that overcome these problems. The result is a more robust version of Everettian quantum mechanics. (shrink)

In her Remarks Upon Some Writers (1743), Catharine Trotter Cockburn takes a seemingly radical stance by asserting that it is possible for atheists to be virtuous. In this paper, I examine whether or not Cockburn’s views concerning atheism commit her to a naturalistic ethics and a so-called radical enlightenment position on the independence of morality and religion. First, I examine her response to William Warburton’s critique of Pierre Bayle’s arguments concerning the possibility of a society of virtuous atheists. I argue (...) that this response shows Cockburn vacillating between a moral naturalism, on the one hand, and a theistic morality, on the other. Second, I draw on Cockburn’s letters to her niece Ann Arbuthnot, and her opinions concerning mystical ideas about “the will of God” in north-east Scotland in the mid-eighteenth century. I maintain that these letters give us a fuller appreciation of Cockburn’s naturalistic position. My conclusion is that Cockburn’s ideas concerning atheism prompt us to consider the close interplay between secular and religious principles in so-called radical ideas of the period. (shrink)

Carmen4.2 is one of the most commented upon of the odes of Horace. It is indeed a complex poem. To summarize roughly: addressing the young poet Iullus Antonius, Horace presents the dangers of emulating Pindar, offering what seems like a lengthy description as well as an approximation of Pindar's own poetic style (1–24). Not as a doomed Icarus imitating the grand Pindaric swan, but in his own preferred mode, like a bee on the banks of Tibur, Horace will continue to (...) produce his own highly refined poems on a small scale (25–30). Iullus Antonius, on the other hand, will sing of Augustus’ triumphmaiore plectro(33, a phrase which in all likelihood refers to his activity as an epic poet). Modestly, Horace himself will be content to join in with the popular chants for Augustus’ triumphal return as one happy civilian among the crowd (33–52). Iullus Antonius will moreover offer a grand sacrifice of ten bulls and as many cows on that occasion, whereas Horace promises a single bull-calf that he is saving especially for the purpose (53–60). I will try to offer a new interpretation of these last two strophes by pointing out an unnoticed allusion to a Hellenistic subtext. (shrink)

Carmen4.2 is one of the most commented upon of the odes of Horace. It is indeed a complex poem. To summarize roughly: addressing the young poet Iullus Antonius, Horace presents the dangers of emulating Pindar, offering what seems like a lengthy description as well as an approximation of Pindar's own poetic style (1–24). Not as a doomed Icarus imitating the grand Pindaric swan, but in his own preferred mode, like a bee on the banks of Tibur, Horace will continue to (...) produce his own highly refined poems on a small scale (25–30). Iullus Antonius, on the other hand, will sing of Augustus’ triumphmaiore plectro(33, a phrase which in all likelihood refers to his activity as an epic poet). Modestly, Horace himself will be content to join in with the popular chants for Augustus’ triumphal return as one happy civilian among the crowd (33–52). Iullus Antonius will moreover offer a grand sacrifice of ten bulls and as many cows on that occasion, whereas Horace promises a single bull-calf that he is saving especially for the purpose (53–60). I will try to offer a new interpretation of these last two strophes by pointing out an unnoticed allusion to a Hellenistic subtext. (shrink)

This article investigates how companies make sense of CSR. It is based on an explorative comparative case study of 18 companies in the Netherlands using background information, interviews and annual reports. Initially, the sensemaking process of CSR is guided and coordinated by change agents who are specifically appointed to explore the implementation of CSR in their company. These change agents initiate the CSR process within their own organisations. The meaning they develop stems from their personal and organisational values and frames (...) of reference. By attuning the vocabulary of CSR to the language of their colleagues, they aim to gain support for this undertaking in their organisation. This sensemaking procedure can be divided into pragmatic, external, procedural, policy‐oriented and value‐driven processes. The capability of an organisation to embed CSR is the result of trial and error, personal preferences and the use of language by the change agent that fits the (dynamic) situation at hand. Thus, each organisation needs a tailor‐made approach to implement CSR successfully. (shrink)

What can contemporary machine learning (ML) models do? Given the proliferation of ML models in society, answering this question matters to a variety of stakeholders, both public and private. The evaluation of models' capabilities is rapidly emerging as a key subfield of modern ML, buoyed by regulatory attention and government grants. Despite this, the notion of an ML model possessing a capability has not been interrogated: what are we saying when we say that a model is able to do something? (...) And what sorts of evidence bear upon this question? -/- In this paper, we aim to answer these questions, using the capabilities of large language models (LLMs) as a running example. Drawing on the large philosophical literature on abilities, we develop an account of ML models' capabilities which can be usefully applied to the nascent science of model evaluation. Our core proposal is a conditional analysis of model abilities (CAMA): crudely, a machine learning model has a capability to X just when it would reliably succeed at doing X if it 'tried'. The main contribution of the paper is making this proposal precise in the context of ML, resulting in an operationalisation of CAMA applicable to LLMs. We then put CAMA to work, showing that it can help make sense of various features of ML model evaluation practice, as well as suggest procedures for performing fair inter-model comparisons. (shrink)

ABSTRACT This article addresses the growing literature in critical race studies, which holds that racism is permanent or incurable, and that by adopting this pessimistic view of racism, we can enact improved and healthier racialized lives. I argue that the focus on curing anti-Black racism, and the failure to do so in the civil rights era and its aftermath has left people of all races, to varying degrees, stuck in pessimistic states of racialized anger, resentment, guilt, and shame. These pessimistic (...) states have brought about an additional level of oppression for targets of racialized oppression. I call it “meta-oppression,” and it is the oppression of being oppressed. I argue that this oppression has exacerbated the effects of the social disease of racism, and it has literally affected the physiologies of many African Americans. This article provides a diagnosis of these existential and physiological states of meta-oppression and a clarification of its characteristics. This diagnosis is an initial step in a larger project of formulating and enacting effective treatments for it. I then argue that meta-oppression is a helpful diagnostic tool for clarifying the characteristics and ramifications on Blacks of US systemic racism during the post–civil rights movement period. I aim to establish meta-oppression as an existential and physiological condition that requires attention so as to expand the social imaginations of people of color and to allow us to engage in more systemic joyful affirmations of our racialized lives while still living within racist conditions. (shrink)

Mary Astell is best known today as one of the earliest English feminists. This book sheds new light on her writings by interpreting her first and foremost as a moral philosopher—as someone committed to providing guidance on how best to live. The central claim of this work is that all the different strands of Astell’s thought—her epistemology, her metaphysics, her philosophy of the passions, her feminist vision, and her conservative political views—are best understood in light of her ethical objectives. To (...) support that claim, this work examines Astell’s programme to bring about a moral transformation of character in her fellow women. This ethical programme draws on several key aspects of seventeenth-century philosophy, including Cartesian and Neoplatonist epistemologies, ontological and cosmological proofs for the existence of God, rationalist arguments for the soul’s immateriality, and theories about how to regulate the passions in accordance with reason. At the heart of Astell’s philosophical system lies a theory of virtue, including guidelines about how to cultivate generosity of character, a benevolent disposition towards others, and the virtue of moderation. This book explains the foundations of that moral theory, and then examines how it shapes and informs Astell’s response to male tyranny within marriage and to political tyranny in the state. It concludes with some reflections on the historiographical implications of writing Mary Astell back into the history of philosophy. (shrink)

Introduction to the book Human Lives: Critical Essays on Conseequentialist Bioethics. This book aims to redress the imbalance in moral philosophy created by the dominance of consequentialism and utilitarianism, the view that criterion of morality is the maximisation of good effects over bad without regard to intrinsic rightness or wrongness. this approach has become the orthodoxy over the last few decades partticularly in bioethics, where moral theory is applied to bioethics. Human Lives critically examines the assumptions and arguemnts of consequentialism (...) reviviing in the process such concepts as rights, justice, innocence, natural integrity, flourishing, the virtues and the fundamental value of human life. (shrink)

Synthetic biology is a broad term covering multiple scientific methodologies, technologies, and practices. Pairing biology with engineering, synbio seeks to design and build biological systems, either through improving living cells by adding in new functions, or creating new structures by combining natural and synthetic components. As with all new technologies, synthetic biology raises a number of ethical considerations. In order to understand what these issues might be, and how they relate to those covered in ethics literature on synbio, we conducted (...) an interview study with practicing synthetic biologists affiliated with a synthetic biology centre in Australia. Scientists identified a range of ethical challenges germane to the field, including precarious employment, pressures from industry, gender inequity, and the negative effects of the hyping of synbio. These challenges differed markedly from those identified in the ethics literature, whose treatment of the harms and benefits of synbio remains largely speculative and abstract. In our discussion of the pragmatic, every day ethical issues synthetic biologists face, we illustrate how issues of waste or research integrity play pivotal roles in everything from lived experiences in the laboratory, to long-term research trajectories guiding the field. In a confirmation of the ethical relevance of our participant’s views on the field, we argue that the subjects they raise must be included in any ethical analysis of synbio as a field. (shrink)

Descriptive accounts of the nature of explanation in neuroscience and the global goals of such explanation have recently proliferated in the philosophy of neuroscience and with them new understandings of the experimental practices of neuroscientists have emerged. In this paper, I consider two models of such practices; one that takes them to be reductive; another that takes them to be integrative. I investigate those areas of the neuroscience of learning and memory from which the examples used to substantiate these models (...) are culled, and argue that the multiplicity of experimental protocols used in these research areas presents specific challenges for both models. In my view, these challenges have been overlooked largely because philosophers have hitherto failed to pay sufficient attention to fundamental features of experimental practice. I demonstrate that when we do pay attention to such features, evidence for reduction and integrative unity in neuroscience is simply not borne out. I end by suggesting some new directions for the philosophy of neuroscience that pertain to taking a closer look at the nature of neuroscientific experiments. (shrink)

People with mental illness are treated, in research, as a ‘class’ or category who are vulnerable, without always being clear why they should be treated as such, not why an individual, rather than the class, is vulnerable. The two main reasons given are lack of competence and power imbalance. Competence issues include incapacity and legislation, assessment and the impact of the illness in decisions. Power issues cover the role of mental health legislation, coercion, protectiveness and paternalism, stigma and discrimination and (...) the ‘well’ and ‘ill’ self. These are examined within a framework of risk assessment, both to the patient and to others. Over-concern to protect the vulnerable can lead to gate-keepers preventing their inclusion in studies at various stages of the research. This denies such groups a voice in the research process.It is suggested that ethical scrutiny of research is not only to prevent harm to the vulnerable, but also to provide a framework to empower such people to take part in research. To do otherwise is to further stigmatize and marginalize them. One way forward is to look at the risk presented by different types of research, from clinical intervention trials to non-therapeutic, qualitative studies and to modify capacity and access requirements in the light of the risks presented. (shrink)

According to some scholars, Mary Astell’s feminist programme is severely limited by its focus on self-improvement rather than wider social change. In response, I highlight the role of ‘virtuous friendship’ in Astell’s 1694 work, A Serious Proposal to the Ladies. Building on classical ideals and traditional Christian principles, Astell promotes the morally transformative power of virtuous friendship among women. By examining the significance of such friendship to Astell’s feminism, we can see that she did in fact aim to bring about (...) reformation of society and not just the individual. (shrink)

This is the second of two collections of correspondence written by early modern English women philosophers. In this volume, Jacqueline Broad presents letters from three influential thinkers of the eighteenth century: Mary Astell, Elizabeth Thomas, and Catharine Trotter Cockburn. Broad provides introductory essays for each figure and explanatory annotations to clarify unfamiliar language, content, and historical context for the modern reader. Her selections make available many letters that have never been published before or that live scattered in various archives, (...) obscure manuscripts, and rare books. The discussions range in subject from moral theology and ethics to epistemology and metaphysics; they involve some well-known thinkers of the period, such as John Norris, George Hickes, Mary Chudleigh, John Locke, and Edmund Law. By centering epistolary correspondence, Broad's anthology works to reframe early modern philosophy, the foundation for so much of twentieth-century philosophy, as consisting of collaborative debates that women actively participated in and shaped. Together with its companion volume, Women Philosophers of Eighteenth-Century England: Selected Correspondence is an invaluable primary resource for students, scholars, and those undertaking further research in the history of women's contributions to the formation and development of early modern thought. (shrink)

Despite a growing body of literature focused on understanding experiences of workplace dignity, attention has centered almost exclusively on employees with lower-level jobs. As a result, little is known about how workplace dignity and indignity are experienced by employees with middle- and upper-level jobs and how their experiences differ from those with lower-level jobs. We address these absences by interviewing employees from a diversity of lower-, middle-, and upper-level jobs about their experiences of indignity at work. We outline common dignity (...) threats, along with typical emotional responses and recourses employees use at each level. We find lower-level employees experience chronic dignity threats from being disrespected, devalued, demeaned, and dehumanized, to which their most typical response is endurance. Middle-level employees experience periodic dignity threats due to undermining of their work, confidence, and reputation. For them, the typical response is strategizing. Finally, on the rare occasions upper-level employees experience dignity threats, it usually is due to a disregard of their special expertise or denial of special rights, to which they respond by rising above. (shrink)

Against the backdrop of the English reception of Locke’s Essay, stands a little-known philosophical dispute between two seventeenth-century women writers: Mary Astell (1666-1731) and Damaris Cudworth Masham (1659-1708). On the basis of their brief but heated exchange, Astell and Masham are typically regarded as philosophical adversaries: Astell a disciple of the occasionalist John Norris, and Masham a devout Lockean. In this paper, I argue that although there are many respects in which Astell and Masham are radically opposed, the two women (...) also have a surprising amount in common. Rather than interpret their ideas solely in relation to the ‘canonical’ philosophies of the time – Lockean empiricism and Malebranchean occasionalism – I examine the ways in which Astell and Masham are influenced by the metaphysical theories of the Cambridge Platonists, Ralph Cudworth and Henry More. On this basis, I argue that a remarkably similar theological approach underlies the metaphysical and feminist arguments of Astell and Masham. (shrink)

Le principe d’induction est lié à la définition des nombres entiers d’une façon à la fois essentielle et sujette à controverse. Fonde-t-il ces nombres, ou bien trouve-t-il en eux son fondement ? Son statut lui-même peut être conçu de diverses manières. Est-il donné par l’expérience, par l’intuition, par la logique, par convention ? Ces questions furent l’objet d’une âpre discussion, autour des années 1905-1906, dans le cadre plus large d’un débat sur les fondements des mathématiques qui opposa Poincaré aux logicistes (...) et aux « axiomatistes » . Nous proposons dans cet article de faire le point sur les termes et les enjeux de cette discussion. Nous montrerons en outre qu’elle fut l’occasion d’une redéfinition de l’analytique et, par suite, des frontières de la logique.The principle of induction is linked essentially to the definition of “integers”, but at the same time has been the subject of controversy : Is the principle founded on integers or, on the contrary, are integers founded on it ? The principle itself can be understood in different ways : as a result of experiment, intuition, logic or convention. These topics were hotly debated in the years 1905-06, in the context of a larger debate on the foundations of mathematics, in which Poincaré opposed the logicists and the “axiomatists” . This article reconsiders what is at stake by looking at the debate in detail and also shows that the debate provided an opportunity for redefining analyticity, and in doing so, redefining the domain of logic. (shrink)

Many political theorists have turned to the dramatic political events of the post-9/11 world – terrorism, war, and the erosion of civil liberties – for insight into our changing sense of the political. Yet few have examined the economic dimensions of these events or sought to learn what they might tell us about the changing nature of political community today. This article seeks to fill this gap by drawing on the work of Michel Foucault and Georgio Agamben to examine the (...) intimate and changing relationship between the political and the economic in the contemporary world. Now more than ever, there is a particular conception of politics at stake in global efforts to govern economic relations. Global economic institutions like the IMF and World Bank are policing the definition of political community and, in doing so, extending the scope of liberal governmentality. At the same time, the character of their implementation and justification is that of the sovereign exception, as state autonomy must continually be breached through extensive conditionality in order for it to be re-established in the form of a more ‘sound’ political and economic order. This is a sovereign exception with a difference: for the norm that is being established is one that necessarily limits the scope of sovereign power in the interests of market freedom. Paradoxically, while the economy is often the exception to politics as usual, is it an exception that simultaneously enables and constrains the possibility of exercising sovereignty itself? (shrink)

This article investigates how companies make sense of CSR. It is based on an explorative comparative case study of 18 companies in the Netherlands using background information, interviews and annual reports. Initially, the sensemaking process of CSR is guided and coordinated by change agents who are specifically appointed to explore the implementation of CSR in their company. These change agents initiate the CSR process within their own organisations. The meaning they develop stems from their personal and organisational values and frames (...) of reference. By attuning the vocabulary of CSR to the language of their colleagues, they aim to gain support for this undertaking in their organisation. This sensemaking procedure can be divided into pragmatic, external, procedural, policy‐oriented and value‐driven processes. The capability of an organisation to embed CSR is the result of trial and error, personal preferences and the use of language by the change agent that fits the (dynamic) situation at hand. Thus, each organisation needs a tailor‐made approach to implement CSR successfully. (shrink)

Before her death in 1673, Margaret Cavendish, the Duchess of Newcastle, expressed a wish that her philosophical work would experience a ‘glorious resurrection’ in future ages. During her lifetime, and for almost three centuries afterwards, her writings were destined to ‘lye still in the soft and easie Bed of Oblivion’. But more recently, Cavendish has received a measure of the fame she so desired. She is celebrated by feminists, literary theorists, and historians. There are regular conferences organised by the International (...) Margaret Cavendish Society, and there have been several biographies, as well as essay collections, journal issues, scholarly editions, and anthologies devoted to her work. In terms of studies in the history and philosophy of science, however, Cavendish has yet to achieve her resurrection in full. While there have been journal articles and book chapters, and a 2001 edition of her Observations, there have been (until now) no book-length studies of her philosophy, and there is currently no modern edition of her other major work, the Philosophical Letters. This essay-length review of Lisa Sarasohn’s The Natural Philosophy of Margaret Cavendish highlights why Cavendish should still hold interest for philosophers today. (shrink)

The purpose of this study is to extend research which has looked at moral judgment. Specifically, the study examines the impact of moral judgment on the budget allocations made by government budget officers. Additionally, and as a result of previous research findings, the study looks at the relationship between political ideology, gender, age, profession and moral judgment.Results support prior research which has found an association between political ideology and moral judgment, and between gender and moral judgment.There was no indication that (...) the level of moral judgment among accountants is different from that of other individuals serving as budget officers, or that age is significantly related to moral judgment. Additionally, the study finds that an individual's level of moral judgment has less of an impact on the individual's actions than does political ideology. Study results contribute to an understanding of the relationship of moral judgment to accounting, and the relationship of moral judgment to behavior. The study also adds to research into the relationship of political ideology and moral judgment. (shrink)

This paper offers a critique of an account of explanatory integration that claims that explanations of cognitive capacities by functional analyses and mechanistic explanations can be seamlessly integrated. It is shown that achieving such explanatory integration requires that the terms designating cognitive capacities in the two forms of explanation are stable but that experimental practice in the mind-brain sciences currently is not directed at achieving such stability. A positive proposal for changing experimental practice so as to promote such stability is (...) put forward and its implications for explanatory integration are briefly considered. (shrink)

In this article, I seek to find a way to reconcile two seemingly irreconcilable concepts. In traditional theology, darkness usually represents something bad, if not downright evil. For the thealogian, however, darkness is an aspect of the Goddess, one that needs to be embraced to achieve whole- ness. I therefore seek a common source in pre-patriarchal texts to suggest a way forward towards acknowledging the wisdom of the Dark Goddess and its value to a world riven by duality.

This article explores how the intersections of gendered, racialized and neoliberal dynamics reproduce social inequality and shape the violence that nurses face. Grounded in the interviews and focus groups conducted with a purposeful sample of 17 registered nurses (RNs) and registered practical nurses (RPNs) currently working in Ontario's mental health sector, our analysis underscores the need to move beyond reductionist notions of violence as simply individual physical or psychological events. While acknowledging that violence is a very real and disturbing experience (...) for individual nurses, our article casts light on the importance of a broader, power structure analysis of violence experienced by nurses in this sector, arguing that effective redress lies beyond blame shifting between clients/patients and nurses. Our analysis illustrates how assumptions about gender, race and care operate in the context of global, neoliberal forces to reinforce, intensify and create, as well as obscure, structural violence through mechanisms of individualization and normalization. (shrink)

Against those who dismiss Kant's project in the "Religion" because it provides a Pelagian understanding of salvation, this paper offers an analysis of the deep structure of Kant's views on divine justice and grace showing them not to conflict with an authentically Christian understanding of these concepts. The first part of the paper argues that Kant's analysis of these concepts helps us to understand the necessary conditions of the Christian understanding of grace: unfolding them uncovers intrinsic relations holding between God's (...) justice and grace. Parts two and three provide an analysis of two concepts of grace used by Kant. Getting clear on their differences is the key to understanding why Kant's account is not Pelagian. (shrink)

Trade treaties and legal agreements generally left Indigenous peoples and colonized communities out of negotiations that directly impacted them. Using Critical Discourse Analysis, informed by decolonial thinking and Nishnaabeg epistemology, this research study analyzed the language of five public documents, published by the World Intellectual Property Organization (WIPO) and the World Trade Organization (WTO), surrounding the protection of Traditional Knowledge (TK) through the _sui generis_ legal figure and its connection to the development of digitization TK. As TK is largely uncommodifiable, (...) the ability to identify and protect TK through Intellectual Property Rights within the WIPO and the WTO is encumbered. The research analyzed and explored how language and knowledge shape policy and ideology against historically marginalized people and communities through discourse enacted by the WIPO and the WTO. (shrink)

Optogenetic techniques are described as “revolutionary” for the unprecedented causal control they allow neuroscientists to exert over neural activity in awake behaving animals. In this paper, I demonstrate by means of a case study that optogenetic techniques will only illuminate causal links between the brain and behavior to the extent that their error characteristics are known and, further, that determining these error characteristics requires comparison of optogenetic techniques with techniques having well known error characteristics and consideration of the broader neural (...) and behavioral context in which the targets of optogenetic interventions are situated. (shrink)

Summary Based on Clausius’ phrasing of a “transformational content” and the resulting 2nd law of thermodynamics, I demonstrated that Gilbert Simondon’s On the Mode of Existence of Technical Objects is historically situated at the threshold of understanding open systems thermodynamics and the related concepts of balance. Furthermore, I showed that Gestalt theory, as represented by Wolfgang Köhler, at least reproduced, if not partially anticipated or even prepared this development of 20th century thinking. Finally, I gave some short examples of how (...) Simondon applied the figure/ground distinction to human perception, memory, and a general theory of becoming and I introduced his proposal to analyse “the grounds” just as thoroughly as the laws of figuration. (shrink)

Tacit knowledge is widely acknowledged to be an important component of innovation, but such recognition is rarely accompanied by more detailed explanations about the nature of tacit knowledge, why such knowledge is significant, how it becomes codified or whether there may be limits to codification. This paper attempts to fill some of the gaps, drawing on a recent study of university/industry links in three emerging technologies. It concludes that tacit knowledge, which can only be transmitted through personal interaction, will continue (...) to play an important role in innovation. This derives from a variety of reasons, but most significant are the complexity of systems and the emergence of new technologies. (shrink)

The escalation of contemporary distress migration has coincided with an intensification of intolerance, xenophobia and nativism precipitating enormous human suffering among the migrant and refugee community. This chapter examines some instances of the growing exclusionary trend in current refugee and migration policy and explores alternative strategic opportunities to enforce the human rights and humanitarian entitlements for distress migrants established by international norms.

For years, legal scholars and environmental activists have maintained that traditional tort proof requirements create insurmountable obstacles to recovery for most plaintiffs in chemical exposure cases, be they pharmaceutical suits or environmental toxic tort cases. Generally, tort law requires a plaintiff to show that the defendant owed a duty, that the defendant breached that duty, and that the breach of that duty caused the injury that is the subject of the suit. In some cases those requirements can be relaxed, as (...) for example, when an injury is of a type that does not occur except as a result of negligence. (shrink)

The three‐dimensional structures adopted by RNA molecules are crucial to their biological functions. The nucleotides of an RNA molecule interact to form characteristic secondary‐structure mctifs. Tertiary interactions orient these secondary‐structure elements with respect to each other to form the functional RNA. Here we describe the basic structural elements with special emphasis on a novel tertiary motif, the pseudoknot.

Nothing could be more private or more social than sex. It is this unique characteristic of human sexual patterns that has resulted in a long and harried controversy among critical social theorists, a controversy largely dominated by white males steeped in the Judaeo-Christian tradition and focused on the significance of sexuality to the revolutionary demand for social and political transformation. Voices from leftist circles have been scattered but loud, ranging from Lenin's straight-laced bunkum, which treated sexuality as an insignificant and (...) at most secondary material need, to Reich's biologism, which pitted the revolutionary potential in the groins of communist youth. (shrink)

Adopting a functionalist perspective, we emphasize the interest of considering imitation as a single capacity with two functions: communication and learning. These two functions both imply such capacities as detection of novelty, attraction toward moving stimuli and perception-action coupling. We propose that the main difference between the processes involved in the two functions is that, in the case of learning, the dynamics is internal to the system constituted by an individual whereas in the case of communication, the dynamics concerns the (...) system composed by the perception of one individual coupled with the action of the other.In this paper, we compare the first developmental steps of imitation in three populations: typically developing children, children with autism, and robots. We show evidence of strong correlations between imitating and being imitated in typical infants and low-functioning children with autism. Relying on this evidence, the robotic perspective is to provide a generic architecture able not only to learn via imitation but also to interact as an emerging property of the system constituted by two similar architectures with a different history. (shrink)

In the course of the human past the elimination of the testicles of boys and men – what we call castration – has taken place for a variety of reasons. Many times it was meant to deliberately hurt people. It is and was also performed, though, as a therapeutic measure by well-meaning physicians. Studying the motivations of medical practitioners involved in castration practices provides insight into the deontology and cultural context of these healers. This article explores the healing activities of (...) the physicians of the ancient Greek and Roman worlds in this special field of surgery. In the extant literary sources we find medical indications for castration which are quite obvious to a modern eye, but also more mysterious and unexpected occasions which need to be explained from the historical context. (shrink)

Samkara has been regarded by many as the most authoritative Hindu thinker of all time. A great Indian Vedantin brahmin, Samkara was primarily a commentator on the sacred texts of the Vedas and a teacher in the Advaitin teaching line. This book serves as an introduction to Samkara's thought which takes this as a central theme. The author develops an innovative approach based on Samkara's ways of interpreting sacred texts and creatively examines the profound interrelationship between sacred text, content and (...) method in Samkara's thought. The main focus of the book is on Samkara's teaching method. This method is, for Samkara, based on the Upanishads' own; it is to be employed by Advaitin teachers to draw pupils skilfully towards that realisation which is beyond all words. Consequently, this book will be of interest not only to students and scholars of Indian philosophy, but to all those interested in the relation between language and that which is held to transcend it. (shrink)

This article examines two early modern feminist works, Woman Not Inferior to Man and Woman's Superior Excellence Over Man, written by “Sophia, A Person of Quality.” Scholars once dismissed these texts as plagiarisms or semi-translations of François Poulain de la Barre's De l’égalité des deux sexes. More recently, however, Guyonne Leduc has drawn attention to the original aspects of these treatises by highlighting Sophia's significant variations on Poulain's vocabulary. In this article, I take Leduc's analysis a step further by demonstrating (...) that Sophia's variations amount to unique and distinctive arguments for the restoration of women's rights, based on both the natural equality and the moral superiority of women compared to men. I argue that Sophia goes beyond Poulain's Cartesian insights to mount a critique of male tyranny characterized as a lack of generosity toward women. My contention is that Sophia's texts represent a culmination in a line of reasoning that extends from the querelle des femmes of the Renaissance to Poulain's Cartesian feminism of the seventeenth century, through to arguments for women's rights in the eighteenth century. Her works thus warrant greater recognition as significant turning points in the history of feminist thought. (shrink)

In this article, I critically examine a number of recent editions of philosophical works by early modern women. I argue that the proliferation of such texts is likely to have positive implications for the study of early modern philosophy. By taking a historical-contextualist approach to women’s writings, these editions contribute to the goal of a thorough, unbiased, and impartial account of early modern thought. Their accessibility and teachability also draw attention to historical-philosophical ideas, methods, and genres that could have worth (...) and relevance today. Above all, these texts are valuable for helping to correct a one-sided, male-biased understanding of the philosophical past. (shrink)